產(chǎn)品名稱：human gene knockout HEK293 cell line
產(chǎn)品規(guī)格：10E6cell/管，2管
產(chǎn)品運(yùn)輸條件：干冰
產(chǎn)品儲(chǔ)存條件和期限：液氮，長(zhǎng)期保存
產(chǎn)品優(yōu)勢(shì)：
? 敲除有保障，無(wú)效退單或重新生產(chǎn)；
產(chǎn)品驗(yàn)收說(shuō)明：
收到細(xì)胞株包裹時(shí)，請(qǐng)立即檢查細(xì)胞株冷凍管是否有解凍情形，若有請(qǐng)立即拍照并通知公司。細(xì)胞株收到后請(qǐng)盡快開(kāi)展實(shí)驗(yàn)，如果想長(zhǎng)期保存請(qǐng)轉(zhuǎn)移至液氮中。
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome.
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