產(chǎn)品名稱：human gene knockout HEK293 cell line
產(chǎn)品規(guī)格：10E6cell/管，2管
產(chǎn)品運(yùn)輸條件：干冰
產(chǎn)品儲(chǔ)存條件和期限：液氮，長期保存
產(chǎn)品優(yōu)勢：
? 敲除有保障，無效退單或重新生產(chǎn)；
產(chǎn)品驗(yàn)收說明：
收到細(xì)胞株包裹時(shí)，請立即檢查細(xì)胞株冷凍管是否有解凍情形，若有請立即拍照并通知公司。細(xì)胞株收到后請盡快開展實(shí)驗(yàn)，如果想長期保存請轉(zhuǎn)移至液氮中。
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3‘-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
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