產(chǎn)品名稱：human gene knockout HEK293 cell line
產(chǎn)品規(guī)格：10E6cell/管，2管
產(chǎn)品運(yùn)輸條件：干冰
產(chǎn)品儲(chǔ)存條件和期限：液氮，長(zhǎng)期保存
產(chǎn)品優(yōu)勢(shì)：
? 敲除有保障，無(wú)效退單或重新生產(chǎn)；
產(chǎn)品驗(yàn)收說(shuō)明：
收到細(xì)胞株包裹時(shí)，請(qǐng)立即檢查細(xì)胞株冷凍管是否有解凍情形，若有請(qǐng)立即拍照并通知公司。細(xì)胞株收到后請(qǐng)盡快開(kāi)展實(shí)驗(yàn)，如果想長(zhǎng)期保存請(qǐng)轉(zhuǎn)移至液氮中。
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5‘ end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
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