+神經(jīng)研究的重要工具——DREADDs技術(shù)
+北大李毓龍研究員課題組開(kāi)發(fā)神經(jīng)遞質(zhì)熒光探針
+維真生物AAV病毒在神經(jīng)中的優(yōu)秀案例分享
+維真生物AAV(retro)產(chǎn)品優(yōu)秀案例分享
1.
Nature Communications. (IF=12.121). Xu, et.al. (2020). CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis.[中國(guó)科學(xué)院昆明動(dòng)物所 AAV9-shRNA(circGRIA1) & AAV9-shRNA(control) 靈長(zhǎng)類(lèi)動(dòng)物恒河猴腦衰老]
2.
Science Advances. (IF=13.116). Sun, et.al. (2020). Development of a CRISPR-SaCas9 system for projection- and function-specific gene editing in the rat brain.[北京大學(xué) CRISPR-saCas9 基因編輯雄性SD大鼠特定神經(jīng)元群]
3.
The Journal of Neuroscience. (IF=5.673). Zingg B, et.al. (2020). Synaptic Specificity and Application of Anterograde Transsynaptic AAV for Probing Neural Circuitry.[南加利福尼亞大學(xué)scAAV1 hSyn-Cre & AAV1-hSyn-Flp & AAVretro-hSyn-Cre & AAV1-EF1a-DIO-Flp-WPRE & AAVretro-hSyn-GFP-WPRE 順向跨單級(jí)突觸示蹤]
4.
Molecular Psychiatry. (IF=12.384). li, et.al. (2020). Programmed cell death 4 as an endogenous suppressor of BDNF translation is involved in stress-induced depression.[山東大學(xué) AAV9-CMV-mPdcd4-P2A-GFP 抑郁癥]
5.
Biological Psychiatry. (IF=12.095). Zhang, et.al. (2020). Reduced neuronal cAMP in the nucleus accumbens damages blood-brain barrier integrity and promotes stress vulnerability.[中國(guó)藥科大學(xué) Dox 誘導(dǎo)性AAV2/9-shRNA-Adcy5 or AAV2/9-shRNA 抑郁癥]
6.
Cell Reports. (IF=8.109). Ma, et.al. (2019). Spontaneous Pain Disrupts Ventral Hippocampal CA1-Infralimbic Cortex Connectivity and Modulates Pain Progression in Rats with Peripheral Inflammation. [北京大學(xué) AAV2 retro-hSyn-Cre-GFP & AAV2-CAG-DIO-BDNF-mCherry-3*flag 慢性疼痛]
7.
Cell. (IF=38.637). Fan, et.al. (2019). Stress-Induced Metabolic Disorder in Peripheral CD4+T Cells Leads to Anxiety-like Behavior. [浙江大學(xué) AAV9-GFAP-GFP-miR30-shRNA(mAdora1) & AAV8-MBP-GFP-miR30-shRNA(mAdora1) & AAV8-MBP-GFP-miR30-shRNA(scramble) 焦慮精神疾病]
8.
Neuron. (IF=14.415). Feng, et.al. (2019). A Genetically Encoded Fluorescent Sensor for Rapid and Speci?c In Vivo Detection of Norepinephrine.[北京大學(xué)AAV9-hSyn-NE1m & NE1h and AAV9-hsyn-tTA 去甲腎上腺素神經(jīng)遞質(zhì)探針]
9.
Cell. (IF=38.637). Sun, et.al. (2018). A Genetically Encoded Fluorescent Sensor Enables Rapid and Speci?c Detection of Dopamine in Flies,Fish, and Mice.[北京大學(xué)AAV-hSyn-DA1m & DA1h 多巴胺神經(jīng)遞質(zhì)探針]
10.
Behavioural Neurology. (IF=2.093). Qu, et.al. (2018). MST1 Suppression Reduces Early Brain Injury by Inhibiting the NF-κB/MMP-9 Pathway after Subarachnoid Hemorrhage in Mice.[第三軍醫(yī)大學(xué)西南醫(yī)院神經(jīng)外科 MST1 AAV-4 in 1 shRNA-GFP 腦室注射 蛛網(wǎng)膜下腔出血]
11.
Neuron. (IF=14.415). Zingg B, et.al. (2017). AAV-Mediated Anterograde Transsynaptic Tagging: Mapping Corticocollicular Input-Defined Neural Pathways for Defense Behaviors.[南加利福尼亞大學(xué)AAV1-EF1a-DIO-Flp 順向跨單級(jí)突觸示蹤]
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